Oral Nanoarmored Live Bacterial Biotherapeutics Bearing Polyphenol-Based Supraparticles Enhance Chemotherapy via Reestablishing Immuno-Oncology-Microbiome Axis

Liu, Qinling; Wu, Yue; Fan, Qingxin; Liu, Jialing; Chen, Yan; He, Yuanmeng; He, Yuanmeng; Wei, Wenqi; Zhang, Haojie; Zhao, Yueling; He, Yunxiang; He, Yunxiang; Du, Xiao; Guo, Junling

doi:10.1021/acsnano.5c01158

Public

Oral Nanoarmored Live Bacterial Biotherapeutics Bearing Polyphenol-Based Supraparticles Enhance Chemotherapy via Reestablishing Immuno-Oncology-Microbiome Axis

Published in ACS Nano • Jun 26, 2025

Authors:

Qinling Liu

Yue Wu

Qingxin Fan

Abstract

The immuno-oncology-microbiome (IOM) axis, referring to the gut microbiota-regulated immune interactions on the tumor microenvironment and systemic immunity, is essential for cancer therapies. However, the cytotoxicity of chemotherapeutic agents (Chemos) disrupts the gut microbiota- and gut microbio...

Subject

Microbiome

Cancer research

Chemotherapy

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!