Euglycemic Diabetic Ketoacidosis Triggered by Sepsis in a Patient on Sodium-Glucose Co-transporter 2 (SGLT2) Inhibitor Therapy: A Case of Diagnostic and Therapeutic Challenges

Ramalingam, Archana; Tewadros, Ayele; De Souza Gonçalves, Bruno; Yelangi, Anitha; Elghul, Ashraf

doi:10.7759/cureus.87029

Public

Euglycemic Diabetic Ketoacidosis Triggered by Sepsis in a Patient on Sodium-Glucose Co-transporter 2 (SGLT2) Inhibitor Therapy: A Case of Diagnostic and Therapeutic Challenges

Published in Cureus • Jun 30, 2025

Authors:

Archana Ramalingam

Ayele Tewadros

Bruno De Souza Gonçalves

Abstract

Euglycemic diabetic ketoacidosis (EDKA) is an uncommon life-threatening condition increasingly recognized in patients treated with sodium-glucose co-transporter 2 (SGLT2) inhibitors. Its diagnosis is often delayed due to the absence of significant hyperglycemia. Sepsis can further complicate the cli...

Subject

Medicine

Diabetic ketoacidosis

Sepsis

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