Retrospective Multicentre Real-Life Study Evaluating the Efficacy of Atezolizumab Combined with Bevacizumab for the Treatment of Metastatic Hepatocellular Carcinoma: HIREAL Study

Barbe-Richaud, Jean-Baptiste; Moinard‐Butot, Fabien; Husson-Wetzel, Stéphanie; Bolliet, Marion; Chiappa, Pascale; Belletier, Christine; Ribeiro, Mathieu; Poprawa, Elodie; Bigot, C.; Abergel, Armand; Ben Abdelghani, Méher

doi:10.2147/jhc.s521130

Public

Retrospective Multicentre Real-Life Study Evaluating the Efficacy of Atezolizumab Combined with Bevacizumab for the Treatment of Metastatic Hepatocellular Carcinoma: HIREAL Study

Published in Journal of Hepatocellular Carcinoma • Jul 1, 2025

Authors:

Jean-Baptiste Barbe-Richaud

Fabien Moinard‐Butot

Stéphanie Husson-Wetzel

Abstract

Background: Hepatocellular carcinoma (HCC) is the most common hepatic malignancy and is one of the most prevalent cancers worldwide. The prognosis of late-stage HCC remains poor. The ImBrave 150 trial successfully demonstrated that overall survival (OS) and progression-free survival (PFS) was improv...

Subject

Atezolizumab

Bevacizumab

Medicine

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