PSA Secretion from Single Circulating Tumor Cells of Metastatic Castration-Naïve Prostate Cancer Patients.

Dathathri, Eshwari; Abali, Fikri; Stevens, Michiel; Booijink, Richell; C van Dijk, Tanja; T Isebia, Khrystany; W M Martens, John; Kraan, Jaco; Beije, Nick; P Lolkema, Martijn; A W Te Boekhorst, Peter; Hamberg, Paul; C M Haberkorn, Brigitte; Houtsma, Danny; van den Bosch, Joan; M van der Deure, Wendy; Bansal, Ruchi; W M M Terstappen, Leon

doi:10.1158/2767-9764.crc-25-0158

Public

PSA Secretion from Single Circulating Tumor Cells of Metastatic Castration-Naïve Prostate Cancer Patients.

Shared by NobleBlocks on Aug 1, 2025 • 12:00 AM UTC

Authors:

Eshwari Dathathri

Fikri Abali

Michiel Stevens

Abstract

PSA is the most common biomarker used in the screening and monitoring of prostate cancer. However, changes in PSA do not always reflect disease dynamics in every patient, and antihormonal agents may modulate its levels without significant antitumor effects. Changes in circulating tumor cells (CTC) h...

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