Omadacycline exhibits anti-inflammatory properties and improves survival in a murine model of post-influenza MRSA pneumonia

Gomi, Sumiko; Price, Emily; Burgoyne, Hailey; Faozia, Sabrina; J. Katahira, Eva; R. McIndoo, Eric; A. Nmaju, Anyauba; Sharma, Kavita; Aghazadeh‐Habashi, Ali; E. Bryant, Amy; L. Stevens, Dennis; V. Pierce, Jessica; W. Serio, Alisa; E. Hobdey, Sarah

doi:10.1128/aac.00469-25

Public

Omadacycline exhibits anti-inflammatory properties and improves survival in a murine model of post-influenza MRSA pneumonia

Published in Antimicrobial Agents and Chemotherapy • Aug 4, 2025

Authors:

Sumiko Gomi

Emily Price

Hailey Burgoyne

Abstract

ABSTRACT Post-influenza Staphylococcus aureus pneumonia, particularly methicillin-resistant S. aureus (MRSA), remains a major cause of mortality, highlighting the urgent need for newer therapeutic options. Omadacycline is an aminomethylcycline antibiotic that has demonstrated efficacy against MRSA a...

Subject

Linezolid

Medicine

Bacterial pneumonia

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