High-Dose Influenza Vaccine to Reduce Hospitalizations

Pardo‐Seco, Jacobo; Rodrı́guez-Tenreiro, Carmen; Giné-Vázquez, Iago; Mallah, Narmeen; Mirás‐Carballal, Susana; Piñeiro-Sotelo, Marta; Cribeiro-González, Martín; Conde-Pájaro, Mónica; González‐Pérez, Juan‐Manuel; Rivero‐Calle, Irene; Bello, Xabier; Lorena Razzini, Josefina; Dacosta-Urbieta, Ana; Salas, Antonio; C. Harris, Rebecca; M. Loiacono, Matthew; van Aalst, Robertus; Manel Farre, Joan; Dufournet, Marine; Dyrby Johansen, Niklas; Modin, Daniel; Biering‐Sørensen, Tor; Durán-Parrondo, Carmen; Martinón‐Torres, Federico

doi:10.1056/nejmoa2509834

Public

High-Dose Influenza Vaccine to Reduce Hospitalizations

Published in New England Journal of Medicine • Aug 30, 2025

Authors:

Jacobo Pardo‐Seco

Carmen Rodrı́guez-Tenreiro

Iago Giné-Vázquez

Abstract

BACKGROUND: Superior protection against laboratory-confirmed influenza has been proved for high-dose inactivated influenza vaccine, as compared with the standard dose, among adults 65 years of age or older. However, data on the relative effectiveness of the high-dose vaccine against severe clinical ...

Subject

Virology

Influenza vaccine

Medicine

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