Influenza vaccine effectiveness and genetic diversity: insights from end-of-season community surveillance, France, 2024–2025

De Clercq, Allan; Blanquart, François; Vieillefond, Vincent; Visseaux, Benoît; Nour Abou Chakra, Claire; C. Nunes, Marta; Jacques, Alexandra; Haïm‐Boukobza, Stéphanie; Wehrle, Valentin; Deleglise, Guillaume; Duret, Thomas; Bernard-Stoecklin, Sibylle; Perez Bercoff, Danielle; Lina, Bruno; Anne Rameix-Welti, Marie; Josset, Laurence; Enouf, Vincent; Bal, Antonin; RELAB study group, The

doi:10.1080/22221751.2025.2562045

Public

Influenza vaccine effectiveness and genetic diversity: insights from end-of-season community surveillance, France, 2024–2025

Published in Emerging Microbes & Infections • Sep 16, 2025

Authors:

Allan De Clercq

François Blanquart

Vincent Vieillefond

Abstract

Influenza 2024-2025 season in France was characterized by prolonged duration, unusual co-circulation of all three viruses (A(H1N1)pdm09, A(H3N2), B/Victoria) with several subclades, and substantial healthcare impact. We aimed to investigate the impact of influenza genetic diversity on vaccine effect...

Subject

Subclade

Medicine

Vaccination

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