Comparative Efficacy and Safety of Anakinra and Canakinumab in Patients With <scp>VEXAS</scp> Syndrome: An International Multicenter Study

Eviatar, Tali; Capelusnik, Dafne; Campochiaro, Corrado; Lacombe, Valentin; Jachiet, Vincent; Zisapel, Michael; Sagy, Iftach; E Tayer-Shifman, Oshrat; Ozeri, David; Kivity, Shaye; Tomelleri, Alessandro; Terrier, Benjamin; Peleg, Hagit; Comont, Thibault; Sacré, Karim; Woaye‐Hune, Pascal; Arnaud, Laurent; Lazaro, Estibaliz; Grobost, Vincent; Lifermann, François; Samson, Maxime; Ardois, Samuel; Garnier, Alice; Maria, A.; Cantagrel, A.; Meyer, A; Bouaziz, Jean‐David; Heiblig, Maël; Dagna, Lorenzo; Diral, Elisa; Kosmider, Olivier; Elkayam, Ori; Hadjadj, Jérôme; Georgin‐Lavialle, Sophie; Fain, O.; Mékinian, A.

doi:10.1002/art.43384

Public

Comparative Efficacy and Safety of Anakinra and Canakinumab in Patients With VEXAS Syndrome: An International Multicenter Study

Published in Arthritis & Rheumatology • Sep 22, 2025

Authors:

Tali Eviatar

Dafne Capelusnik

Corrado Campochiaro

Abstract

OBJECTIVE: The aim of this study was to compare differences in clinical response, drug survival, and adverse event rates between anakinra and canakinumab in VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome. METHODS: This multicenter international study includes patients with...

Subject

Medicine

Canakinumab

Anakinra

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