Herpesviruses Reactivation and Systemic Inflammation Before and After Initiating Antiretroviral Therapy Among Women with HIV in Rakai, Uganda

Ssempijja, Victor; Callier, Viviane; Nason, Martha; Anok, Aggrey; Lisco, Andrea; D Redd, Andrew; C Quinn, Thomas; Rupert, Adam; Towlerton, Andrea; Das, Sanchita; Walker, Lorenzo; Tomusange, Stephen; Kityamuweesi, Taddeo; Bbuule, Paul; Sereti, Irini; J Reynolds, Steven

doi:10.1093/ofid/ofaf603

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Herpesviruses Reactivation and Systemic Inflammation Before and After Initiating Antiretroviral Therapy Among Women with HIV in Rakai, Uganda

Shared by NobleBlocks on Sep 28, 2025 • 12:00 AM UTC

Authors:

Victor Ssempijja

Viviane Callier

Martha Nason

Abstract

Abstract Introduction The association of mucosal shedding of human simplex virus (HSV)-2, Kaposi’s sarcoma-associated herpesvirus (KSHV) and cytomegalovirus (CMV) after antiretroviral therapy (ART) initiation in women-living-with-HIV (WLWH) with systemic inflammation is unclear. Methods We recruited...

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