The Ultrastructural Properties of the Endoplasmic Reticulum Govern Microdomain Signaling in Perisynaptic Astrocytic Processes

Denizot, Audrey; Fernanda Veloz Castillo, Marı́a; Puchenkov, Pavel; Calì, Corrado; De Schutter, Erik

doi:10.1002/glia.70091

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The Ultrastructural Properties of the Endoplasmic Reticulum Govern Microdomain Signaling in Perisynaptic Astrocytic Processes

Shared by NobleBlocks on Oct 16, 2025 • 12:00 AM UTC

Authors:

Audrey Denizot

Marı́a Fernanda Veloz Castillo

Pavel Puchenkov

Abstract

ABSTRACT Astrocytes are now widely accepted as key regulators of brain function and behavior. Calcium (Ca 2+ ) signals in perisynaptic astrocytic processes (PAPs) enable astrocytes to fine‐tune neurotransmission at tripartite synapses. As most PAPs are below the diffraction limit, their content in C...

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