Haemodynamic Changes After Prophylactic Doses of Ephedrine, Phenylephrine, Norepinephrine Versus Placebo During Induction of General Anaesthesia: A Randomised Trial

Helge Sjøen, Gunnar; Hugo Hauge, Tor; Sørum Falk, Ragnhild; Inge Tønnessen, Tor; Langesæter, Eldrid

doi:10.1111/aas.70138

Public

Haemodynamic Changes After Prophylactic Doses of Ephedrine, Phenylephrine, Norepinephrine Versus Placebo During Induction of General Anaesthesia: A Randomised Trial

Published in Acta Anaesthesiologica Scandinavica • Oct 27, 2025

Authors:

Gunnar Helge Sjøen

Tor Hugo Hauge

Ragnhild Sørum Falk

Abstract

BACKGROUND: Ephedrine, phenylephrine, and norepinephrine are commonly used to manage hypotension during the induction of anaesthesia. The objective of this study was to evaluate whether prophylactic administration of assumed equipotent doses of these vasopressors could maintain systolic arterial blo...

Subject

Medicine

Anesthesia

Placebo

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