Determining the role of pregnancy-induced IgG antibodies in parity-associated mammary oncoprotection 3099

Anandan, Dhivyaa; C. Trousdell, Marygrace; Varshini, Amritha; Somasundara, Hanasoge; T.‐H. Yeh, Johannes; O. dos Santos, Camila

doi:10.1093/jimmun/vkaf283.937

Public

Determining the role of pregnancy-induced IgG antibodies in parity-associated mammary oncoprotection 3099

Published in The Journal of Immunology • Nov 1, 2025

Authors:

Dhivyaa Anandan

Marygrace C. Trousdell

Amritha Varshini

Abstract

Abstract Description An early first pregnancy reduces lifelong risk for breast cancer (BC) by ∼30%, partly due to pregnancy-induced changes to mammary immunity. Plasma cells (PCs) and memory B cells (mBCs) accumulate in the mammary gland (MG) during pregnancy and lactation. We are investigating whet...

Subject

Mammary gland

Antibody

Biology

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