Prediction of lung cancer using volatile biomarkers in breath1

Phillips, Michael; K. Altorki, Nasser; H. M. Austin, John; B. Cameron, Robert; N. Cataneo, Renee; Greenberg, Joel; Kloss, Robert; A. Maxfield, Roger; I. Munawar, Muhammad; I. Pass, Harvey; Rashid, Asif; N. Rom, William; Schmitt, Peter

doi:10.3233/cbm-2007-3204

Public

Prediction of lung cancer using volatile biomarkers in breath1

Published in Cancer Biomarkers • Apr 25, 2007

Authors:

Michael Phillips

Nasser K. Altorki

John H. M. Austin

Abstract

BACKGROUND: Normal metabolism generates several volatile organic compounds (VOCs) that are excreted in the breath (e.g. alkanes). In patients with lung cancer, induction of high-risk cytochrome p450 genotypes may accelerate catabolism of these VOCs, so that their altered abundance in breath may prov...

Subject

Lung cancer

Receiver operating characteristic

Medicine

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