A guided chatbot-based psychological intervention for psychologically distressed older adolescents and young adults: a randomised clinical trial in Jordan

A. Bryant, Richard; M. de Graaff, Anne; Habashneh, Rand; Fanatseh, Sarah; Keyan, Dharani; Akhtar, Aemal; Abualhaija, Adnan; Faroun, Muhannad; Said Aqel, Ibrahim; Dardas, Latefa; Afar, Hadeel; Servili, Chiara; Hadži-Pavlović, Dušan; VAN OMMEREN, M.; Carswell, Kenneth

doi:10.1038/s41746-025-02142-8

Public

A guided chatbot-based psychological intervention for psychologically distressed older adolescents and young adults: a randomised clinical trial in Jordan

Published in npj Digital Medicine • Jan 15, 2026

Authors:

Richard A. Bryant

Anne M. de Graaff

Rand Habashneh

Abstract

This randomised controlled trial compared a 10-session chatbot intervention with 5 weekly brief support calls (STARS) to enhanced usual care (EUC) in distressed young adults in Jordan (N = 344). Primary outcome was change in anxiety and depression severity assessed at baseline by the Hopkins Symptom...

Subject

Anxiety

Depression (economics)

Intervention (counseling)

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