Integrated Skin Sensitization Assessment Using Consensus Modelling and Tiered New Approach Methodology: A SaferSkin Case Study

P. Ankli, Pascal; Mohoric, T.; Parween, Shaheena; Lopez, Béatrice; Daligaux, Pierre; Darde, Thomas; Chesné, Christophe; Stockman, N.; Milhomem Lemos, Jade; Saiakhov, Roustem; Boglári, Csaba; Y. Poon, Amanda; C. Ukaegbu, Daniel; Horta Andrade, Carolina; Hardy, Barry

doi:10.64898/2026.03.15.711911

Public

Integrated Skin Sensitization Assessment Using Consensus Modelling and Tiered New Approach Methodology: A SaferSkin Case Study

Published in bioRxiv (Cold Spring Harbor Laboratory) • Mar 18, 2026

Authors:

Pascal P. Ankli

T. Mohoric

Shaheena Parween

Abstract

Abstract The transition toward animal-free safety assessment of chemicals has accelerated the development of New Approach Methodologies (NAMs) for predicting skin sensitization. However, individual in silico models and experimental NAM assays frequently produce inconsistent or contradictory results,...

Subject

Probabilistic logic

Workflow

Computer science

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