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Effect of neonatal handling on age-related impairments associated with the hippocampus.

Published in Science (New York, N.Y.) • Feb 12, 1988
Authors:
M J Meaney
,
D H Aitken
,
C van Berkel

Abstract

In rats, an environmental manipulation occurring early in life resulted in changes in the adrenocortical axis that persisted throughout the entire life of the animals and attenuated certain deficits associated with aging. Rats handled during infancy had a permanent increase in concentrations of rece...

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