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A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

Published in Science • Aug 17, 2012
Authors:
Martin Jinek
,
Krzysztof Chylinski
,
Ines Fonfara

Abstract

Ditching Invading DNA Bacteria and archaea protect themselves from invasive foreign nucleic acids through an RNA-mediated adaptive immune system called CRISPR (clustered regularly interspaced short palindromic repeats)/CRISPR-associated (Cas). Jinek et al. (p. 816 , published online 28 June; see the...

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