The influence of finasteride on the development of prostate cancer.

M Thompson, Ian; J Goodman, Phyllis; M Tangen, Catherine; Scott Lucia, M; J Miller, Gary; G Ford, Leslie; M Lieber, Michael; Duane Cespedes, R; N Atkins, James; M Lippman, Scott; M Carlin, Susie; Ryan, Anne; M Szczepanek, Connie; J Crowley, John; A Coltman, Charles

doi:10.1056/nejmoa030660

Public

The influence of finasteride on the development of prostate cancer.

Published in The New England journal of medicine • Jul 17, 2003

Authors:

Ian M Thompson

,

Phyllis J Goodman

,

Catherine M Tangen

Abstract

BACKGROUND: Androgens are involved in the development of prostate cancer. Finasteride, an inhibitor of 5alpha-reductase, inhibits the conversion of testosterone to dihydrotestosterone, the primary androgen in the prostate, and may reduce the risk of prostate cancer. METHODS: In the Prostate Cancer P...

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