Multicenter randomized trial of adjuvant fluorouracil and folinic acid compared with surgery alone after resection of colorectal liver metastases: FFCD ACHBTH AURC 9002 trial.

Portier, Guillaume; Elias, Dominique; Bouche, Olivier; Rougier, Philippe; Bosset, Jean-François; Saric, Jean; Belghiti, Jacques; Piedbois, Pascal; Guimbaud, Rosine; Nordlinger, Bernard; Bugat, Roland; Lazorthes, Franck; Bedenne, Laurent

doi:10.1200/jco.2006.06.8353

Public

Multicenter randomized trial of adjuvant fluorouracil and folinic acid compared with surgery alone after resection of colorectal liver metastases: FFCD ACHBTH AURC 9002 trial.

Published in Journal of clinical oncology : official journal of the American Society of Clinical Oncology • Nov 1, 2006

NobleIDark:/48914/w1/20260526/EF0FC4CFRecord on NobleID

Authors:

Guillaume Portier

,

Dominique Elias

,

Olivier Bouche

Abstract

PURPOSE: Complete resection of liver metastases of colorectal origin is the only potentially curative treatment. In order to decrease recurrences, the use of adjuvant systemic chemotherapy after liver resection is controversial because no randomized study demonstrated its benefit. PATIENTS AND METHO...

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