Evolution of pathogenicity and sexual reproduction in eight Candida genomes.

Butler, Geraldine; D Rasmussen, Matthew; F Lin, Michael; A S Santos, Manuel; Sakthikumar, Sharadha; A Munro, Carol; Rheinbay, Esther; Grabherr, Manfred; Forche, Anja; L Reedy, Jennifer; Agrafioti, Ino; B Arnaud, Martha; Bates, Steven; J P Brown, Alistair; Brunke, Sascha; C Costanzo, Maria; A Fitzpatrick, David; W J de Groot, Piet; Harris, David; L Hoyer, Lois; Hube, Bernhard; M Klis, Frans; Kodira, Chinnappa; Lennard, Nicola; E Logue, Mary; Martin, Ronny; M Neiman, Aaron; Nikolaou, Elissavet; A Quail, Michael; Quinn, Janet; C Santos, Maria; F Schmitzberger, Florian; Sherlock, Gavin; Shah, Prachi; A T Silverstein, Kevin; S Skrzypek, Marek; Soll, David; Staggs, Rodney; Stansfield, Ian; P H Stumpf, Michael; E Sudbery, Peter; Srikantha, Thyagarajan; Zeng, Qiandong; Berman, Judith; Berriman, Matthew; Heitman, Joseph; A R Gow, Neil; C Lorenz, Michael; W Birren, Bruce; Kellis, Manolis

doi:10.1038/nature08064

Public

Evolution of pathogenicity and sexual reproduction in eight Candida genomes.

Published in Nature • Jun 4, 2009

NobleIDark:/48914/w1/20260526/155ABA29Record on NobleID

Authors:

Geraldine Butler

,

Matthew D Rasmussen

,

Michael F Lin

Abstract

Candida species are the most common cause of opportunistic fungal infection worldwide. Here we report the genome sequences of six Candida species and compare these and related pathogens and non-pathogens. There are significant expansions of cell wall, secreted and transporter gene families in pathog...

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