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Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options.

Published in Current neuropharmacology • Mar 1, 2009
Authors:
Bayani Uttara
,
Ajay V Singh
,
Paolo Zamboni

Abstract

Free radicals are common outcome of normal aerobic cellular metabolism. In-built antioxidant system of body plays its decisive role in prevention of any loss due to free radicals. However, imbalanced defense mechanism of antioxidants, overproduction or incorporation of free radicals from environment...

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