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Fast and sensitive protein alignment using DIAMOND.

Published in Nature methods • Jan 1, 2015
Authors:
Benjamin Buchfink
,
Chao Xie
,
Daniel H Huson

Abstract

The alignment of sequencing reads against a protein reference database is a major computational bottleneck in metagenomics and data-intensive evolutionary projects. Although recent tools offer improved performance over the gold standard BLASTX, they exhibit only a modest speedup or low sensitivity. ...

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