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Cytokines in clinical cancer immunotherapy.

Published in British journal of cancer • Jan 1, 2019
Authors:
Pedro Berraondo
,
Miguel F Sanmamed
,
María C Ochoa

Abstract

Cytokines are soluble proteins that mediate cell-to-cell communication. Based on the discovery of the potent anti-tumour activities of several pro-inflammatory cytokines in animal models, clinical research led to the approval of recombinant interferon-alpha and interleukin-2 for the treatment of sev...

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